| We are
sure by now you have heard about Paylean™. If not, it is time that
you learn what your competition is feeding? Paylean™ is the
most talked about feed additive on the show circuit since L-Carnitine
and Chromium Picolinate were introduced. It is also one of the
most misunderstood additives as well. We hope the following
information helps answer some of your questions on how and why
Paylean™ increases Fat Free Lean Growth by 34%.
What
is Paylean™?
First, let’s
look at what Paylean™ is. Paylean™ is a feed additive containing
Ractopamine Hydrochloride. In the scientific world it is classified as
a member of a class of compounds called Phenethanolamines or
Beta-Agonists. It is also referred to as a repartitioning agent in
that it takes nutrients away from fat deposition and puts or directs
them toward lean tissue (muscle) accretion. Contrary to popular belief
it is not a steroid, hormone, or antibiotic.
Does
Paylean™ have any feeding restrictions?
We are sure you have heard of
many different feeding restrictions with Paylean™. Just to set the story
straight here they are directly from Elanco, the company that produces
Paylean™:
- Paylean™ can be fed from 4.5 to 18 grams/ton of complete feed
- Paylean™ is labeled for use in pigs weighing from 150 to 240 lb
- Paylean™ does not require a withdrawal prior to slaughter
- Paylean™ should be fed in a diet containing at least 16% crude
protein.
- Elanco recommends feeding Paylean™ during the last six weeks (last
90 lb of gain) prior to slaughter
- Currently, no feed grade medications are approved to be fed in
combination with Paylean™. However, injectable or water soluble
antibiotics may be administered to pigs being fed Paylean™.
- Currently, Paylean™ is not cleared for use in breeding animals. In
tests, gilts fed Paylean™ during the finishing period only, had
similar results in a subsequent breeding, gestation, and lactation
period as controls.
How
does Paylean™ work in the animal’s body?
Sometimes people say a picture
is worth a thousand words. Probably the best way to describe how Paylean™
works is shown in the picture below. Simply put, Phenethanolamines like
Paylean™ speed up the rate fat is released or burned (from adipose or
fat cells) and decrease the rate of fat deposited. What this does is makes
nutrients more available to the nutrient pool which can be used for
protein synthesis and muscle growth. Thus, pigs fed Paylean™ become
heavier muscled and leaner at the same time.

Taken from Anderson et al. (1991).
What
are the typical responses we can expect by using Paylean™?
One thing is clear, Paylean™
works! Scientific studies have shown Paylean™ increases lean muscle and
average daily gain, decreases the fat content of carcasses and improves
feed efficiency. In addition, since Paylean™ makes pigs more efficient,
pigs don’t consume as much feed. Typical results of feeding Paylean™
are shown below:
Summary of Paylean™
response.*
|
Response |
Percent Improvement |
|
Increased fat-free lean growth |
34.0% |
|
Increased protein accretion |
24.0% |
|
Decreased feed intake |
5.5% |
|
Increased Average daily gain |
8.9% |
|
Improved F/G |
14.2% |
|
Reduced backfat thickness |
13.7% |
|
Increased dressing percentage |
1.5% |
Values taken from Schinckel and
Richert, 2000. *18.0 g/ton level for the last 90 lbs of live weight gain.
At
what level and when is the best time to feed Paylean™?
If you don’t remember
anything else from this page, please remember the following information.
How one feeds Paylean™ and at what level is a decision that should not
be taken lightly. How much Paylean™ one offers a pig will depend
upon the amount of muscle a pig already possesses. Dose response
research shows pigs offered 4.5 gram/ton have close to 70-80% of the
response in loin eye area and up to 50% of the response in backfat depth
compared to pigs fed the 18 g/ton level. Pigs fed at 9.0 grams/ton
level performed intermediate to pigs fed at 4.5 and 18 grams/ton (Schinckel
and Richert 2000). If you already have an extremely muscled show pig, you
might want to consider feeding the 4.5 gram/ton rate initially. If
one feeds the 18 grams/ton rate you may create such a heavy muscled pig
that he will appear "freakish" to a judge. You may create
what some judges refer to as "this pig having too much muscle in
relation to his frame size". If you have a heavy muscled pig and can
only purchase complete feed with 18g/ton of Paylean™ you might want to
reconsider your thinking. Don’t worry, later we have a solution
for both the heavy and light muscled pigs.
| |
|
|
Ractopamine Level, g/ton |
|
|
Response |
0 |
4.5 |
9 |
18 |
|
ADG, lbs/day |
1.80 |
1.98 |
1.99 |
2.01 |
|
10th rib fat depth, in. |
.99 |
.94 |
.92 |
.87 |
|
Loin Eye Area, sq. in. |
5.15 |
5.55 |
5.7 |
5.84 |
Walkins et al., 1988, 6 trials,
888 pigs.
Another important point to remember is the lean growth response to
Paylean™ is not constant over the entire 90 lb gain feeding period. The
response increases, reaches a plateau, and then declines with the maximum
response being achieved at 22-26 lbs of live weight gain or approximately
9-24 days on Paylean™ at the 18 grams/ton (Williams et al., 1994).
As you can see, pigs fed increasing levels of Paylean™ have a
significant increase in lean growth rates and a general reduction in feed
intake. These facts alone suggest pigs receiving Paylean™ will require
more nutrients to optimize muscle growth. Next, let’s discuss what these
key nutrients are.
Do
you need to feed a higher level of crude protein and amino acids when
feeding Paylean™?
Yes,
Paylean™ must be fed in a diet with a minimal of 16% crude
protein. One of the reasons the FDA implemented this requirement
is based upon recent research data showing Ractopamine does not work
as effectively when an animal is fed a standard finishing ration
(below 16% crude protein). This is demonstrated in research by
Adeola and Young, 1989. They fed finishing pigs diets with
either 13 or 17% crude protein and 0 or 18 grams/ton ractopamine (see
table below). Feeding ractopamine depressed growth and feed
efficiency in pigs fed 13% protein diets, but improved growth and feed
efficiency in those fed 17% crude protein.
Interaction of Paylean™
and protein content*.
|
Protein, % |
13 |
13 |
17 |
17 |
|
Paylean™, 18 grams/ton |
0 |
18 |
0 |
18 |
|
ADG, lb |
2.12 |
1.94 |
2.16 |
2.42 |
|
F/G |
3.33 |
3.7 |
3.33 |
2.70 |
*Adeola and Young, 1989.
Thus, to obtain the maximum protein deposition rates from Paylean™,
pigs must be fed diets with protein (amino acid) concentrations higher
than those presently recommended for finisher pigs during the last 90
lbs of weight gain. Later we will show you how to obtain these
important amino acids for muscle growth.
Does
the pig’s Lysine requirement increase?
Yes, Elanco recommends the
total dietary lysine levels be increased by up to 25%. This is
dependent upon which phase of the finishing phase your animals are in
and which level of Paylean™ you are feeding.
Does
Paylean™ influence the energy needs of a pig?
We know that muscle
development requires the proper amounts and balance of amino acids but
as equally important requires adequate energy. Pigs depositing large
amounts of muscle require a high level of energy in the diet.
Therefore, the expectation might be that when pigs are treated with
Paylean™, they would require increased energy to support the
increase in muscle development. However, current data are somewhat
inconclusive.
Does
Paylean™ influence the vitamin requirements of a pig?
Based on current available
data we cannot arrive at a clear answer. However, research in lean
growth genotype pigs has shown better responses with higher levels of
vitamin supplementation. Research in chickens using a compound similar
to Ractopamine has demonstrated that added thiamin to diets helps to
increase the response of phenethanolamines (Hamano et al., 1999).
Does
Paylean™ influence the mineral requirements of a pig?
There is currently no data
that address the calcium and phosphorus requirement of pigs offered
Paylean™. However, ractopamine has been reported to lower the bone
content of pigs, expressed as an individual bone weight and accretion
rate per day. (Bark, 1990).
Efficacy of ractopamine in
pigs of low and high genetic capacity for lean growth.
|
Lean growth genotype: |
|
Low |
|
High |
|
Ractopamine, g/ton: |
0 |
18 |
0 |
18 |
|
Bone, kilograms |
13.00 |
12.34 |
20.94 |
19.40 |
|
Bone, grams/day |
22 |
17 |
56 |
45 |
Bark, 1990. Study involved
72 pigs from 140 to 230 lbs bodyweight.Effect of ractopamine
(P<.04) for bone weights and (P<.11) for the accretion rate of
bone (gram/day).
Based upon these data one might expect that pigs fed Paylean™ may
have an increased requirement for calcium and phosphorus.
Are you Confused?
As you can see, Paylean™ is a technically advanced product. If
all of this confuses or scares you, don’t worry, we have a solution.
We pride ourselves in putting together supplement products that make
feeding advanced technologies like Paylean™ easy, convenient, and
cost effective. Click
here if you are interested in seeing Premier Nutrition’s solution.
Conclusion
We hope we have contributed to your knowledge of feeding Paylean™
to your livestock project. One thing is clear, Paylean™ should be
viewed as a management tool to enhance the genetic potential of your
animal. It is not a so-called "magic pill" and will never
replace good genetics or proper management. If you have
additional questions about Paylean™ please give us a call at
806-481-2000 or email us at info@pntechologies.com. |